CyPhyLab – CPL | BIAS
FG Bio-inspirierte Architektur und Sensorik
Prof. Liss C. Werner
Faculty VI | Institut für Architektur
Technische Universität Berlin
A30 | Lab Raum 609
Office Management Raum 805
Straße des 17. Juni 152
DE-10623 Berlin

“the architect is no longer an organizer of matter and space but a designer of systems –
with multi-layered components and complex relationships”



CPL BIAS | The CyPhyLab – laboratory for cyber-physical systems in architecture and urban design is an interdisciplinary research entity engaging with architecture as a changing profession that opens formerly unknown fields of research. It describes the foundations of the Chair of  Bio-Inspired Architecture and Sensoric at the Institute of Architecture, Technische Universität Berlin. Our agenda is ‘Humanification of Technology’. We operate along cybernetic principles and combine them with established architectural practice. This results in a convergence of space, biology, material and cyber-physical systems. We aim at an architecture where biology and the digital is connected with the physical materials and the smart objects in the networked world of the internet of things. The CyPhyLab was founded by Prof. Liss C. Werner in 2018 and became the chair of Bio-Inspired Architecture and Sensoric in 2020 and consists of an interdisciplinary and international team. The CyPhyLab is mainly funded through H2020 third party funds.


A concrete application for architecture is to create buildings that act and interact with people and the environment. We want our buildings to become familiar with our human behaviour and to behave accordingly. Within our discipline of architecture we work in the field of biological computing, material behaviour and sensor technology. Our plan is to integrate networked intelligence into our built environment. We use tools like scripting and programming, as well as methods from artificial intelligence (e.g., pattern recognition), combined with material intelligence for architecture. Topics such as Human-Machine-Networks (HMN) and Human Computer Interaction (HCI) drive our work. For architecture, this is still basic research. Especially, since we have the ambition to design buildings architecturally very well. The process from (parametric) design to computer controlled production, construction and evaluation is part of this task. Our prototypes and artefacts are guided by the “Closed Loop Digital Design Process” we developed in 2018.


We aim at a post-digital Sixth Ecology, where the virtual digital, material analog and the evolutionary biological elements converge into, for example, learning systems. The digital cannot be separated from our material world anymore. It is integrated in our physical human bodies as it is integrated in our buildings, cities and urban infrastructures. What began in the 1940s with control engineering at selected universities (including the TU Berlin) is now being implemented across the board. We create a truly cybernetic reality controlled by neural networks, whose cognitive nature is hardly distinguishable from a biological one. We follow cybernetic principles and method to enable emergent systems and space. We are trying to understand what it means to be digital and how we can create a digital physicality. We call the process of getting there cybernetification.

Research + Academia




Noise Optimisation for Incubators, Innovation Spaces and Environments (NOIISE) improves productivity and comfort in open plan work spaces. Co-funded by H2020 EIT Digital 2019, ID19393.



EZY-CRD-GO is a research-based design project partially funded by the European Union. Aim is to provide a safe entry- and exit strategy, before, during, and after a temporary event in a public or semi-public space. The IoT solution combines non-invasive WiFi crowd monitoring with efficient wayfinding and crowd guidance solutions.


Get Home Safely

GetHomeSafely is looking into an application of 5G enabled IoT devices used for guiding humans through dark areas. Co-funded by H2020 EIT Digital 2019, ID19053


BrightAgeing - Human Centric Lighting

BrightAgeing is investigating the impact of light temperature and color onto the indiovidual human stress level. We developed an app to connect Philips Hue Lights to a heart-rate-variability measuring deice. Co-funded by H2020 EIT Digital 2018, ID18124.


Built by Data

Built by Data aims at closing gaps in the digital workflow from design to material choice, production, construction and maintenance for the architecture- and construction industry. We developed a) a post-occupancy survey app to analyze human comfort and b) a process for a 2,5-dimensional parametric modular facade to enhance visual comfort. Co-funded by H2020 EIT Digital 2018, ID18101.


Phy is an ongoing research on the biological organism Physarum Polycephalum. We are observing and simulating its behavior, learn about the principles and finally use them to push architecture and urban design towards the bio-inspired and intelligent. Research is in collaboration with Tactile Architecture


Classes taught in the CyPhyLab engage with Material Behaviour and Material Intelligence. Through experimental research, we start understanding the possibilities for its application on a variety of levels and scale. The critical discussion about our novel human/machine relation in an urban IoT (Internet of Things) environment is central to the work.


Urban and architectural design strategies are experiencing a paradigm shift. In 1974 Constantinos A. Doxiadis stated “At present we are in the middle of the greatest ecological crisis. This is the crisis which started two centuries ago when humanity entered the era of applied science and industry.“ In 1997, during the first digital turn in architecture, Stan Allen contributed to an understanding of architecture as systemic field rather than an agglomeration of discrete objects, leading to an investigation of design methods based on biological principles paired with cybernetic concepts. In the studio we will develop and design cities of morphing ecologies. Our cities will be systemic in nature – embracing humans and no-humans alike, computationally generated urban landscapes of formally alien beauty. Our decisions will be driven by the UN sustainability goals set by the 2030 agenda for Sustainable Development. Tiny intro to bio-inspiration.

Image credit: Antonio Maria Leicht and Niki Sidirourgou

Image credit: Liss C. Werner

Learning Outcomes: At the end of the semester you will know a bit better how biology works, geometries in nature are generated based on specific rules and logics and how you can translate this into computational making of architecture. Technically you will also have learned of how to digitally fabricate your bio-inspired modules. As an add on, you will have gained an insight into the terminology and theory of computational (digital, parametric) architecture.

Design Outcome: Modular objects leading to morphogenetic landscapes for our urban environment. Functions are up to your ideas.

Exhibited at the Venice Biennale 2021 as part of CityX.

Modul: Städtebau, Hochbau
Quispos: XXXX, SWS, LP
Course start: planned November 03rd 2020, Thursday 14:00-18:00

Registration to be announced

Location: United Universe of Architecture
Teaching Team: Prof. Liss C. Werner, Assist. Valmir Kastrati


Bio-inspired modular morphologies are understood as 2- to 3-dimensional aggregated geometries based on biological principles. Morphogenesis, driven through a multitude of parameters such as material behavior and humidity, is the bio-computer generating the form of a static or kinetic structure. We will use this design strategy to examine material; leading to the design of topographies, modular landscapes and objects. Methods: observation, analysis, analog folding, digital 3D-printing, biological growing. Ad-on: computational theory in architecture. Tiny intro to bio-inspiration.

Pearl_Nautica source

Learning Outcomes: At the end of the semester you will know a bit better how biology works, geometries in nature are generated based on specific rules and logics and how you can translate this into computational making of architecture. Technically you will also have learned of how to digitally fabricate your bio-inspired modules. As an add on, you will have gained an insight into the terminology and theory of computational (digital, parametric) architecture.

Design Outcome: Modular objects leading to morphogenetic landscapes for our urban environment. Functions are up to your ideas.

Modul: Aspekte städtebaulicher Analyse und Entwurfsmethodik
Quispos: 4584, 4SWS, 6LP
Course start: planned May 05th 2020, each Tuesday 16:30-18:30

Registration via ISIS, OR at

Location: United Universe of Architecture
Teaching Team: Liss C. Werner, Valmir Kastrati

Architekturtheorie/Kritik II, Analog loves Digital I Post-digital Theory: learning from a Pioneer seminar on and conversation with Peter Eisenman, IDs2345645, 32020.

Urban Material Intelligence XS-XL, #VI, Sensoric Urban Prototypes, Interaction, Modularity – Material Behavior through Geometry, From Bits to Light. ID40425.

Studio Werkstatt Berlin- Malaysia, Biennal 100YC with D. Köring, I. M. Pienaru, IDs 234558, 40405. Results were presented at the Venice Architecture Biennale 2018 as part of 100 year city.

Thesis supervision, Slawomir Klyszcz “Disruptive Future Cities” with Prof. R. Bunschoten and Prof. Dr. I. Borrego

Urban Material Intelligence XS-XL #IV,V, Sensoric urban Prototypes, Interaction, Modularity – Material Behavior through Geometry, BuiltbyData. ID40425.

Taught Research Project, Speculative Urbanism, ID40435

Communicating Architecture, ID24010

Studio Digital Forefront with Prof. R. Bunschoten, D. Köring, IDs 234558, 40405

Urban Material Intelligence XS-XL #II, III, Sensoric urban Prototypes, Interaction, Modularity – Material Behavior through Geometry, ID 40425

Studio City Lab – City Maker, Tempelhof and Berlins Housing Crisis with Prof. R. Bunschoten, IDs 234558, 40405


S. H. Khajavi, N. H. Motlagh, A. Jaribion, L. C. Werner and J. Holmström, “Digital Twin: Vision, Benefits, Boundaries, and Creation for Buildings” in IEEE Access, vol. 7, pp. 147406-147419, 2019.
doi: 10.1109/ACCESS.2019.2946515

Werner, L. C. (2019). Disruptive Material Intelligence of Physarum: Liquid Architecture of a Biological Geometry Computer. In: Adamatzky, A. (Ed.): Slime Mould in Art and Architecture, Chapter: 14, River Publishers, pp.227

Werner, L. C.: The Origins of Design Cybernetics. In: Fischer, T. / Herr M., C. (eds.): Design Cybernetics: Navigating the New. Springer International Publishing AG, 2019

Werner, L. C. / Adamatzky, A. (eds.): Proto-Architecture and Unconventional Biomaterials. Special Issue: biomimetics, mdpi, Basel, forthcoming 2019. ISSN 2313-7673;

CONVERSATIONS Vol. I.: Cybernetics: state of the art. Berlin: Universitätsverlag der Technischen Universität Berlin, 2017
ISBN: 978-3-7983-2954-6 (online), 978-3-7983-2953-9 (print) DOI: 10.14279/depositonce-6121 (CON-VERSATIONS)

Adamatzky, A., Szacilowski, K., Przyczyna, D., Konkoli, Z., Sirakoulis, G C.., Werner, L. C.: On buildings that compute. A proposal. In: Adamatzky, A., Kendon, V. (eds.): From Astrophysics to Unconventional Computing. Festschrift to Susan Stepney. Springer, forthcoming 2019 – currently available preprint on arxiv

Werner, L. C.: CYBERNETIFICATION I: Cybernetics Feedback Netgraft in Architecture. In: Werner, L. C. (ed.): CONVERSATIONS. Cybernetics: state of the art. Berlin: Universitätsverlag der Technischen Universität Berlin, 2017, ISBN (print) 978-3-7983-2953-9  ISBN (online) 978-3-7983-2954-6, DOI 10.14279/depositonce-6121 (CON-VERSATIONS)

Werner. L. C.: Kybernetisches Zeich[n]en – Feedback between Gordon Pask and Frieder Nake [DE], Cybernetic Drawing – Feedback between Gordon Pask and Frieder Nake [EN], In: Vito Cardone (ed.): diségno N. 3, Biannual Journal of the UID – Unione Italiana par il Disegno Scientific Society. Rom: Unione Italiana per il Disegno, 2018, ISSN: 2533-2899

Werner, L. C.: Form and Data-from linear Calculus to cybernetic Computation in Interaction. In: Sousa, P. J. et al (eds.): Architecture in the Age of the 4th Industrial Revolution. Proceedings 36th eCAADe-Conference, Volume tbc. Porto: Porto University, 2019, pp. tbc. ISBN tbc – 09/2019

Werner, L. C.: Biological Computation of Physarum – from DLA to spatial adaptive Voronoi. In: Kępczyńska-Walczak, A. et al (eds.): Computing for a better tomorrow. Proceedings 36th eCAADe-Conference, Volume 2. Lodz: Lodz University of Technology, 2018, pp.535-536. ISBN 978-94-91207-16-7, DOI 10.14279/depositonce-7675

Werner, L. C.: HUNCH 1972: A Second Experiment in Sketch Recognition or: ‘I Know the Concept of Your Concept of interpolation’. In: Marcos, Carlos L. (ed.): Graphic Imprints: The Influence of Representation and Ideation Tools in Architecture. Proceedings XVII EGA International Conference. University of Alicante, Spain. Cham: Springer International Publishing, 2018, p. 3-11.

ISBN (print): 978-3-319-93748-9 ISBN (online): 978-3-319-93749-6DOI
Download Link:

Werner, L. C.: A Cloud recycling Light: human feedback matters. In: Trento, A. et al (eds.): ShoCK – Sharing of Computable Knowledge. Proceedings 35th eCAADe, Education and Research in Computer Aided Architecture and Design in Europe. Rome: La Sapienza University Press, 2017, p. 699-708.
ISBN 978-3-642-23435-4 (online),
978-36-422-3434-7 (print)
DOI: 10.1007/978-3-642-23435-4_8

For the complete list of publication click here



Alexander Brauer, Maximilian Quick, Moritz Funck, Merriam Berrima, Niki Apostolopoulou, Victor Xian-Hao Li, Doan Ba Thinh Nguyen, Marie Le Péchon, Bryan Varela, Clément Bacquet, Slawomir Klyszcz, Inês Costa Ferreira, Izabela Kutyla, Marta Mazur, Ran Li, Tomas Barbera Ramallo, Luke Hannaford, Zhang zhaoxi, Tan Jingwei, Yunke Zheng, Polina Sevostianova, Guilherm Zanoli, Antoine Bechet


Minoo Heidari Tabar, Anna-Maria Chatzi, Lonna Al Bondakji, Lisa-Marie Wesseler, Joan Gukens Valero, Pombo Goncalo, Macur Makysmilian, Katarzyna Raczkowska, Kin Chung Marco Lau, Liam Patterson, Maria Porras Varo, Noemi Gonzales, Fujii Ryuta, Theresa Lohse, Huichao Ding, Ye Wenqia, Nan Bai, Jianan Li


Zahide Gülsah Durmaz, Narjes Ghashghaei, Undine Kimmel, Theresa Lohse, Maksymilian Macur, Louai Sameh Mesharrafa, Omar Osman Abdelhamid, Katarzyna Obarzanowska, Dayana Born, Seungak Kook, You Xiaohui, Katrina Kim, Andrés Reyes Kutscher, Carla Rojas, Eduardo Brizio, Fernanda Seoane Gomez, Ayda Grisiute, Pinelopi-Filothei Karali


Bengisu Aydos, Tunca Beril Barasan, Daniel Base, Elif Civici, Esra Cümert, Mohsen Khanmohamadi, Joanna Malgorzata Kowalik, Anastasia Kuznetsova, Antonia Maria Leicht, Fatemeh Norouzzadehmahboob, Heiko Rehage, Mauritz Severin Renz, Amirhossein Rezaeicherati, Niki Sidirourgou, Merlina Stephens Dupeyron, Sebastian Johannes von Stosch, Zitong Ye

Liss C. Werner

Professor and Chair for Bio-inspired Architecture and Sensoric, CyPhyLab| BIAS
MArch UCL, DipArch UCL, Bahons University of Westminster London
Architect AK Berlin, RIBA |, ||
Director Tactile Architecture - Büro für SystemArchitektur
CEO UnIMas Universe by Intelligent Machines

Suryaveer Patnaik

Data Analysis and Development
Project Assistant, Research Assistant
MBA Building Sustainability
Dipl. Renewable Eergy, TERI BArch Chitkara
Architect PGD

Theresa Lohse

Digital Fabrication
Research Assistant
BSc Beuth Hochschule für Technik
Ma Architecture, Technische Universität Berlin

Valmir Kastrati

Bio-Computation and Digital Architecture
Project Assistant, Research Assistant
MArch Hochschule Anhalt
BSc Universiteti i Prishtinës

Martin Baier

Research Support and Websites
Student Project Assistant
BSc Architecture TU Berlin (enrolled)
Media Designer (digital & print)

Dr. Dietmar Koering
Dr.-Ing. Dietmar Koering

New Technologies and Ethics
Postdoc Guest Researcher
MArch UCL, Dipl.-Ing. Architektur
Muthesius Kunsthochschule Kiel
Architekt BDA, AK NRW, Director Arphenotype

Carmen Preuß

Manager External Funds
A5, Technical Group Fine Arts
Faculty VI
Institute of Architecture

Liss C. Werner
Chair and Professor of  Bio-Inspired Architecture and Sensoric
MArch UCL, DipArch UCL, Bahons University of Westminster London, Architect AK Berlin, RIBA |, ||

Liss C. Werner is the founder and Lab Leader of the CyPhyLab,  Chair of  Bio-Inspired Architecture and Sensoric CPL | BIAS. She is a registered architect at the architect’s registration board Berlin, Germany. Werner acted as visiting Professor at Carnegie Mellon University (2012) and adj assoc. Professor at Taylor’s University, Malaysia (2014-2016), ran the Master Studio Codes in the Clouds at DIA Dessau (2010-2016), lectured internationally at e.g., MIT, CalArts, USC, Texas Tech, The Bartlett, Syracuse University, Cooper Union, Nottingham Trent University, Kassel University, ESARQ, University Innsbruck, is regularly invited as jury member and peer-reviewer and publishes widely on cybernetics and architecture. She is a member of the American Society of Cybernetics Independent Expert Evaluator for the European Commission for Horizon 2020 proposals. Links: Google Scholar. ORCID.


Pawel Unger, Scripting and Moving Image
Intern, in cooperation with Tactile Architecture, 2019

Pedro Soares, Product Design and Visualization
Intern, in cooperation with Tactile Architecture, 2019

Stefanie Holzheu, Media Architecture and Sensoric
Research Assistant, M.S. Architecture (SUNY),
M.Sc. MediaArchitecture, Dipl.-Ing. Architecture, 2018

Sarath Sasidharan, Data Analytics
Student Project Assistant, 2018

Mouhamad Sobh, Graphics and Communication
Student Project Assistant, B.Arch, 2018


Prof. Liss C. Werner

CyPhyLab | BIAS
Technische Universität Berlin
Fak VI | Institut für Architektur
A30 | Lab Raum
Office Management Raum 805
Straße des 17. Juni 152
DE-10623 Berlin

+49 30 314-26122